Antibacterial Activity of the Flavonoid, patulitrin isolated from the flowers of Tagetes erecta L

نویسنده

  • S. Madhavan
چکیده

Fresh flowers of Tagetes erecta L., the flavonoid was isolated by extraction and fractionation with different solvents. It was then identified as patulitrin (10mg/100ml) by various tests. It was then subjected to disc diffusion assay to assess its antibacterial potentials against Alcaligens faecalis, Bacillus cereus, Campylobacter coli, Escherchia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Proteus vulgaris, Streptococcus mutans and Streptococcus pyogenes. The flavonoid possesses antibacterial activity against all the tested strains and shows maximum zone of inhibition for Klebsiella pneumoniae (29.50 mm). T.erecta flavonoid patulitrin is one of the potential elements for therapeutic use.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Appraisal of biological activities and identification of phenolic compound of African marigold (Tagetes erecta) flower extract.

The flowers of African marigold (Tagetes erecta L), a medicinal plant widely cultivated in Thailand, were subjected to evaluation for total phenolics, DPPH scavenging and thiobarbituric acid-reactive substance (TBARs) assays as well as tyrosinase inhibitory activity. In preliminary studies, the ethyl acetate (EA) extract obtained by continuous extraction showed the highest activities with highe...

متن کامل

PETAL SENESCENCE IN CUT Tagetes erecta L. FLOWERS: ROLE OF PHENOLICS

Petals are an excellent model system for the study of fundamental aspects of senescence. The need of present study was felt with the aim to study the changes taking place during petal senescence in cut flowers of Tagetes erecta L. Estimation of total phenols was studied from first stage to senescent stage of Tagetes erecta L. The amount of total phenols had a decreasing trend with progressing s...

متن کامل

Effects of Flavonoids from French Marigold (Florets of Tagetes patula L.) on Acute Inflammation Model

The major components patuletin and patulitrin were isolated from French marigold (florets of Tagetes patula). Patuletin and patulitrin were found to inhibit acute inflammation in mice. Oral administration of patuletin and patulitrin significantly suppressed hind-paw edema induced by carrageenin and histamine, while topical application of patuletin and patulitrin significantly inhibited ear edem...

متن کامل

Antimicrobial Efficacy of Different Solvent Extracts of Tagetes erecta L. Flower, Alone and in Combination with Antibiotics

Bacteria have evolved numerous defences against antimicrobial agent and drug resistance in pathogen is on rise. This is due to rapid development of multi-drug resistance, limited anti-bacterial spectrum and adverse effects of available anti-microbial agents. This necessitates the search for new antimicrobials with diverse structures and novel mechanism of action. Flowers are mostly used for orn...

متن کامل

Tagetes erecta Linn. and its mosquitocidal potency against Culex quinquefasciatus.

OBJECTIVE To investigate mosquitocidal effects of ethanolic extract of flowers of Tagetes erecta (T. erecta) and its chloroform and petroleum ether soluble fractions against the larvae of Culex quinquefasciatus (Cx. quinquefasciatus). METHODS The fresh flowers of T. erecta were extracted in cold with ethanol (5.0 L) and after concentration, the ethanol extract was fractionated with chloroform...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2011